In patients with heart failure, serious adverse events and adverse events leading to discontinuation of study medication in merit-hf at an incidence greater than or equal to 1 in the group receiving toprol-xl and greater than placebo by more than 0.

Information about Toprol.

TOPROL-XL 47.5 tablets are white to off-whiteroundscored on one side and marked A/mO on the other sideThe score line is only there to help you break the tablet if you have difficulty swallowing it whole.

Do not use TOPROL-XL to treat any other complaints unless your doctor tells you to.

Shortness of breathbeing less able to exercise swelling of the anklesfeet or legs chest tightnesswheezingnoisy breathingdifficulty breathing chest painchanges in heart rate or palpitations swelling of the facelipstongue or throat which may cause difficulty in swallowing or breathingwhich may be signs of a serious allergic reaction yellowing of the skin or eyesjaundicegenerally feeling unwell.

HypotensionTreat underlying bradycardiaConsider intravenous vasopressor infusionsuch as dopamine or norepinephrine.

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking TOPROL-XL.

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metoprolol blocks the action of the sympathetic nervous system, a portion of the involuntary nervous system, by blocking beta receptors on sympathetic nerves.