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Safe and effective use of lincomycin is not established for infants of age less than 1 month old.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Lincocin and other antibacterial drugsLincocin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteriaWhen culture and susceptibility information are availablethey should be considered in selecting or modifying antibacterial therapyIn the absence of such datalocal epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

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Patients with severe impairment of renal function and/or abnormal hepatic function should be dosed with caution and serum lincomycin levels monitored during high-dose therapysee DOSAGE AND ADMINISTRATION

WARNINGBlack BoxRare but sometimes fatal intestinal problems have occurredpseudomembranous colitiswith use of lincomycinThereforeit should only be used to treat serious infections where less toxic antibiotics are not appropriateIt should not be used to treat nonbacterial infections such as upper respiratory infections.

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