For every occurrence of diarrhea on clindamycin, discontinue and give vancomycin.

Information about Clindamycin.

GastrointestinalAbdominal painpseudomembranous colitisesophagitisnauseavomitingand diarrheasee BOXED WARNINGThe onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatmentsee WARNINGSEsophageal ulcer has been reportedAn unpleasant or metallic taste has been reported after oral administration.

Clindamycin can cause diarrheawhich may be severe or lead to seriouslife-threatening intestinal problemsIf you have diarrhea that is watery or bloodystop using this medicine and call your doctor.

Keep all appointments with your doctor and the laboratoryYour doctor may order certain lab tests to check your body’s response to clindamycin.

To make sure clindamycin is safe for youtell your doctor if you have ever had:

Hypersensitivity ReactionsGeneralized mild to moderate morbilliform-likemaculopapularskin rashes are the most frequently reported adverse reactionsVesiculobullous rashesas well as urticariahave been observed during drug therapySevere skin reactions such as Toxic Epidermal Necrolysissome with fatal outcomehave been reportedSee WARNINGSCases of Acute Generalized Exanthematous PustulosisAGEPerythema multiformesome resembling Stevens-Johnson syndromeanaphylactic shockanaphylactic reaction and hypersensitivity have also been reported.

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smx-tmp doxycycline clindamycin if strep is also a distinct possibility, use clindamycin.