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Other drugs may interact with metaxaloneincluding prescription and over-the-counter medicinesvitaminsand herbal productsTell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Do not drink alcoholDangerous side effects or death can occur when alcohol is combined with SkelaxinCheck your food and medicine labels to be sure these products do not contain alcohol.
SKELAXINmetaxaloneis indicated as an adjunct to restphysical therapyand other measures for the relief of discomforts associated with acutepainful musculoskeletal conditionsThe mode of action of this drug has not been clearly identifiedbut may be related to its sedative propertiesMetaxalone does not directly relax tense skeletal muscles in man.
Serotonin syndromeSSwhich is potentially life-threateninghas been reported with metaxalone useThese reports generally occurred when metaxalone was used concomitantly with serotonergic drugssuch as tramadol or selective serotonin reuptake inhibitorsSSRIsor when metaxalone was used at doses higher than the recommended dosesee DRUG INTERACTIONS and OVERDOSAGESigns of SS may include clonusagitationdiaphoresistremorhyperreflexiahypertoniaand temperature elevation.
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