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The cdc also recommends isoniazid 15 mg kg rounded to the nearest 50 or 100 mg; max 900 mg po in combination with rifapentine once weekly for 12 weeks under directly observed therapy dot , which is equal to the 9-month daily isoniazid regimen.
Information about Isoniazid.
It is not known whether isoniazid will be harmful to an unborn babyDo not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
Contact your doctor immediately if you experience numbness or tingling in the hands or feetweaknessfatigueloss of appetitenausea and vomitingyellowing of the skin or eyesor darkening of the urine.
Serum concentrations of hepatic transaminases should be monitored whenever possible.
Take the missed dose as soon as you rememberIf it is almost time for the next regularly scheduled doseskip the missed dose and take the next one as directedDo not take a double dose of this medication.
It is rapidly absorbed and diffuses readily into all fluids and tissuesThe plasma half-lifewhich is genetically determinedvaries from less than 1 hour in fast acetylators to more than 3 hours in slow acetylatorsIt is largely excreted in the urine within 24 hoursmostly as inactive metabolites.
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